The University of Guanajuato was founded in 1732. Since then, it has adopted several names until March 1945, when the rank of University was acquired, and the name is now known.

UG is a major research institution with 106 graduate and 98 undergraduate programs in the fields of Arts, Health Sciences, Economics and Administration Sciences, Natural and Exact Sciences, Social Sciences and Humanities, Life Sciences, and Engineering. UG has a total enrollment of 30,936 students, in 4 Campuses across Guanajuato State, organized in 13 Divisions and 52 departments. The UG High School System has 17,144 students in 11 venues in the state of Guanajuato.

UG has over 330 laboratories and 637 researchers who have been recognized by the National System of Researchers of the Mexican Council of Science Humanities and Technology (CONAHCYT)

 Research is carried out by Research Groups creating an ideal environment for knowledge production, management, and technology transfer. UG also organizes every year its Summer Research Program, recognized internationally for its quality, offered to undergraduate and graduate students.

In terms of international collaboration, UG has 323 international agreements with 201 international partners in 35 countries. It offers double degree programs at the undergraduate and graduate level.